Look Before You Leap: Test for Mimics of Small Vessel Primary Angiitis of the CNS Before Jumping to Brain Biopsy
Winter 2023 | CNS Connections magazine
Mimics of pediatric small vessel primary angiitis of the central nervous system. CM Stredny, MM Blessing, V Yi, et al. Annals of Neurology 2023;93:109-119. What the researchers did: Primary angiitis...
Levetiracetam and Phenobarbital are Equal (and weak) in Efficacy for Neonatal Seizures
Winter 2023 | CNS Connections magazine
Levetiracetam versus phenobarbital for neonatal seizures: A retrospective cohort study. L. Battig, C. Dunner, D Cserpan et al. Pediatric Neurology 2023;138:62-70. What the researchers did: As all pediatric neurologists know,...
Unraveling the Complex Interplay Among Epilepsy, Cognitive Impairment, and Sleep Disruption
Winter 2023 | CNS Connections magazine
Throughout most of medical history, epilepsy has been considered principally a problem of seizures. However, in recent years, the fact has become clear that epilepsy is more than just a...
The Importance of Intracellular Chloride Concentration and Neuronal Volume in Neonatal Seizures.
Spring/Summer 2019 | CNS Connections magazine
Neonatal seizures are a pernicious problem confronting child neurologists. While they are common and cause substantial morbidity, their pathophysiology is poorly understood. Most of the treatments for neonatal seizures consist...
Focus on Young Researchers: Development of a Simple Blood Test for Mitochondrial Disorders
Spring/Summer 2018 | CNS Connections magazine
As all child neurologists know, “mitochondrial disorder” is frequently on the differential diagnosis for many children with neurological disease. However, determining whether a patient actually has a mitochondrial disorder is...